磁共振灌注成像在脑膜瘤诊断中的应用研究

Exploratory Development of MR Perfusion Weighted Imaging in Diagnosis Meningeomas of Typing and Grading Before Operation

目的探讨磁共振(MR)灌注成像技术对脑膜瘤术前分型及良恶性鉴别的临床应用价值。方法对47例脑膜瘤病人行MR灌注成像检查,对5种亚型的良性脑膜瘤的MR灌注成像进行分析,并与非典型性及恶性脑膜瘤进行比较。结果血管瘤型脑膜瘤实质部分的rCBV值均数最高,恶性组脑膜瘤的rCBV值均数最低。各亚型间瘤体实质最大rCBV值均数间差异有统计学意义(P<0.05),良恶性脑膜瘤实质部分最大rCBV值均数间差异有统计学意义(P<0.05)。瘤周水肿区的rCBV值均数间差异无统计学意义(P>0.05)。结论rCBV值对脑膜瘤术前分型及良恶性鉴别有所帮助,而瘤周水肿区的rCBV值对脑膜瘤分型及良恶性鉴别未显示临床实用价值。

Objectlve To evaluate the role of MR Perfusion Weighted Imaging in preoperation diagnosis of meningiomas. Methods MR Perfusion Weighted images was performed in 47 patients with meningiomas followed by conventional imaging. Results The mean rCBV values of angioblastic was the highest in the parenchyma of tumor. The mean rCBV values of malignant group was the lowest. The biggest mean rCBV values among different type meningiomas was statistically significant. The biggest mean rCBV values between benign and malignant group meningiomas was statistically significant, but not in the peri - tumor edema. Conclusion The rCBV values were useful in the preoperative differentiation diagnosis of different types of meningiomas. Those in the peri - tumor edema were useless in the preoperative differentiation diagnosis of different types of meningiomas.