肝病患者血浆D-D、FDP测定的临床意义

Clinic Significance of Measuring the Plasma D-D and FDP of Hepatopath

目的:探讨肝脏疾病时凝血和纤溶系统的活动状态及其临床意义。方法:肝病组与正常对照组D-D和FDP指标比较,并进行统计学处理及t检验。结果:与对照组比较各肝病组的D-D和FDP均有显著性的差异,其阳性率依次为重症肝炎>肝硬化>肝癌>慢性肝炎>急性肝炎,尤其以重肝、肝硬化和肝癌更为显著。结论:检测血浆FDP和D-D水平,对肝病的疗效观察、预后判断、早期发现隐匿型DIC、原发性或继发性纤溶具有重要的临床应用价值。

Objective：To discuss the active state of blood clotting and fibrolysis system of patients with liver diseases and its clinic significance. Methods：The levels of D-D and FDP between the groups with liver diseases and normal control were compared and analysed. Results：The levels 0f D-D and FDP of the groups with liver diseases were significantly different from the normal control. The positive ratios in turn were serious hepatitis〉cirrhosis〉liver eancer〉chronic hepatitis〉acute hepatitis, especially high in the serious hepatitis group, cirrhosis group and the liver cancer groups. Conclusion： Detecting the values of plasm D-D and FDP is very valuable in curative effect overview of hepatopathy and its prognosis,and in early discovery of the delitescenceDIC, the primarily and secondary fibrolysis.