1Alter MJ. Epidemiology and prevention of hepatitis B[J]. Semin Liver Dis, 2003, 23(1):39-46.
2Heider U, Fleissner C, Zavrski I,et al. Treatment of refractory chronic lymphocytic leukemia with Campath-1H in combination with lamivudine in chronic hepatitis B infection[J]. Eur J Haematol, 2004, 72(1):64-66.
3Conjeevaram HS, Lok AS. Management of chronic hepatitisB [J]. J Hepatoh 2003, 38 Suppl:90-103.
5Marcellin P, Maria H, Sacks SL,et al. A phase Ⅱ dose-escalating trial of clevudine in patients with chronic hepatitis B[J]. Hepatology, 2004, 40(1):140-148.
2DE MAN RA,WOLTERS LMM,NEVENS F,et al.Safety and efficacy of oral entecavir given for 28 days in patients with chronic hepatitis B virus infection[J].Hepatology,2001,34(3):578 -582.
3WOLTERS LMM,HANSEN BE,NIESTERS HGM,et al.Viral dynamics during and after entecavir therapy in patients with chronic hepatitis B[J].J Hepatol,2002,37(2):137-144.
4COLONNO RJ,GENOVESI EV,MEDINA I,et al.Long-term entecavir treatment result in sustained antiviral efficacy and prolonged life span in the woodchuck model of chronic hepatitis infection[J].J Infect Dis,2001,184 (10):1236-1245.
5MARION PL,SALAZAR FH,WINTERS MA,et al.Potent efficacy of entecavir(Bms-200475) in a duck model of hepatitis B virus replication[J].Antimicrob Agents Chemother,2002,46(1):82 -88.
6JULANDER JG,COLONNO RJ,SIDWELL RW,et al.Charaterization of antiviral of entecavir in transgenic mice expressing hepatitis B virus[J].Antiviral Res,2003,59(3):155-161.
7HONKOOP P,DEMAN RA.Entecavir:a potent new antiviral drug for hepatitisB[J].Expert Opin Investig Drugs,2003,12(4):683 -688.
8LAI CL,ROSMAWATIM,LAO J,et al.Entecavir is superior to lamivudine in reducing hepatitis B virus DNA in patients with chronic hepatitis B infection[J].Gastroenterology,2002,123(6):1831-1838.
9CHANG T.Entecavir is superior to lamivudine for the treatment of HBeAg (+) chronic hepatitis B:results of phase Ⅲ study ETV-022 in nucleoside-naive patients[J].Hepatology,2004,40(4 Suppl 1):193A
10SHOUYAL D.Entecavir demonstrates superior histologic and virologic efficacy over lamivudine in nucleoside-naive HBeAg (-)chronic hepatitis B:results of phase Ⅲ trial ETV-027[J].Hepatology,2004,40(4 Suppl 1):728A.
