参芪止血胶囊止血作用的实验研究

Experiment on antihemorrhagic effect of Shen Qi Zhi Xue Capsule

目的观察参芪止血胶囊止血的作用机制。方法以雌性SD大鼠为研究对象，将其随机分为正常组，参芪止血胶囊低、中、高剂量组（以下简称参低、中、高组）和宫血宁组。测定大鼠出血时间（BT），凝血时间（CT），凝血酶原时间（PT）和活化部分凝血活酶时间（APTT）并进行比较分析。结果与正常组比较，参芪止血胶囊能够显著缩短BT、CT、PT和APTT的时间（P〈0．05，P〈0．01），与宫血宁组比较，参中组缩短BT、CT上有统计学意义。结论参芪止血胶囊能有效止血。

Objective To observe the antihemorrhagic effect of Shcn Qi Zhi Xue Capsule. Methods Randomized 50 female SD rats into the control group, Gong Xue Ning Capsule group, low, medium and high dosage of Shen Qi Zhi Xue Capsul group（low, medium and high desage group for short）. Bleeding time（BT）, clotting time（CT）, prothrombin time（PT） and activating partial thremboplastin time（APTT）were tested and compared. Results Compared with the control group, Shen Qi Zhi Xue Capsule could effectivel reduce BT, CT, PT and APTT（P 〈0.05 or P〈0.01）. Compared with Gong Xue Ning Capsule group, medium dosage of Shen Qi Zhi Xue Capsule could obvionsly reduce BT and CT（P〈0.05）. Conclusion Shen Qi Zhi Xue Capsule had an obvionsly antihemorrhagic function.