足月新生儿缺氧缺血性脑病一周内CT分度诊断指标的研究

The study of CT scoring target in neonates hypoxic-ischemic encephalopathy

目的探讨1周内正常新生儿与足月新生儿缺氧缺血性脑病患儿（HIE）颅脑CT影像学特点。方法对108例正常新生儿和173例HIE患儿行颅脑CT扫描，取特定的扫描层面及位置，双侧对称检测脑实质密度的CT值。结果正常新生儿灰质密度CT值范围20—28Hu；HIE轻度CT值范围17—20Hu，中度14—17Hu，重度14Hu以下。结论出生1周内正常新生儿与HIE患儿颅脑CT值测量指标对HIECT诊断具有重要意义。

Objective To study the CT features and its corretation of normal neonates and neonatal hypoxic-ischemie encephalopathy. （HIE）. Methods 108 cases of normal neonate brains were scanned, the CT ralne of bilateral cerebral of related slices. On this basis, a quantitative classification criteria was made for 173 eases of neonatal HIE. Results The CT value normal neonates of were ranging from 27 - 39 Hu for cerebral cortex and from 20 to 28 Hu for cerebral medulla. Neonates with HIE could be classified into three degrees aecording to CT value（ 17 - 19 Hu for gentle degree, 14 - 16. 9 Hu for moderate degree and below 14 Hu for serere degree）. Conclusion The measuring CT value of cerebral cortex and medulla for normal neonates and neonatal HIE can play a significant role in clinical diagnosis of HIE .