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内质网应激在2型糖尿病发病及治疗中的作用 被引量：1

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摘要 糖尿病（DM）是严重危害人类健康的常见病，目前全世界有1亿7千万DM患者．预计在未来25年内DM患者将达到3亿6千万。临床上DM主要分为1型糖尿病（T1DM）和2型糖尿病（T2DM），而T2DM占DM的90％～95％。T2DM是以骨骼肌、肝脏及脂肪等胰岛素靶组织胰岛素抵抗为主要特征。他DM的发病机制目前尚不完全清楚，近年来研究表明内质网应激可以促进胰岛素抵抗和B细胞凋亡，同时也出现了一些改善内质网应激的治疗方法。从而促进T2DM病的转归。现综述如下。
作者 冷一平 海春霞
机构地区 中南大学药学院药理教研室
出处 《现代医药卫生》 2008年第22期3402-3404,共3页 Journal of Modern Medicine & Health
关键词 2型糖尿病 内质网应激 发病机制 治疗方法 胰岛素抵抗 T2DM 1型糖尿病 人类健康
分类号 R587.1 [医药卫生—内分泌] R363.27 [医药卫生—病理学]
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参考文献19

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同被引文献26

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现代医药卫生
2008年 第22期

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