^(18)F-FDG PET/CT标准摄取值诊断口腔颌面部鳞癌及颈转移癌的研究

Standard uptake value of ^(18)F-FDG in diagnosis of oral squamous cell carcinoma and cervical lymphonode metastatic squamous cell carcinoma

目的:探讨18F-FDGPET/CT融合显像的标准摄取值SUV在口腔颌面部鳞癌及转移癌诊断中的价值。方法:本研究选取23例口腔颌面部鳞癌及颈转移癌患者,进行18F-FDGPET/CT全身显像,并进行病理检查。结果:18F-FDGPET/CT诊断头颈鳞状细胞癌及颈转移癌的灵敏度100%,特异度80%,准确性91.30%。高中分化鳞癌组、低分化鳞癌组、非癌组织组SUV值差异有统计学意义(F=32.77,P<0.05)。两两比较差异亦有统计学意义(P<0.01)。结论:18F-FDGPET/CT标准摄取值诊断口腔颌面部鳞癌及颈转移癌有重要价值。

Objective：To evaluate the diagnosis value of standard uptake value（SUV）of 18F-fluorodeoxyglucose（18F-FDG）in oral squamous cell carcinoma and cervical lymph node metastatic squamous cell carcinoma.Methods：Twenty three patients with oral squamous cell carcinoma and cervical lymph node metastatic squamous cell carcinoma were under gone 18F-FDG PET/CT imaging.All cases were comfirmed histopathologically.Results：The sensitivity,specificity,and accuracy of SUV in diagnosis of oral squamous cell carcinoma and cervical lymph node metastatic squamous cell carcinom were 100%,80%,and 91.30% respectively.The SUV in 3 group high and media differentiated squamous cancer,lowr differentiated squamous cancer,and non malignant tisseue were different through F test（F=32.77,P〈0.05）.q test（P〈0.01）.Conclusions：It is a very useful modality for diagnosis of oral squamous cell carcinoma and cervical lymph node metastatic squamous cell carcinoma.