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多囊卵巢综合征相关基因研究进展 被引量：1

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摘要 多囊卵巢综合征（PCOS）是育龄期妇女最常见的内分泌疾病之一，其主要表现为月经稀发或闭经、不孕、卵巢多囊性变、肥胖、多毛、高雄激素血症和胰岛素抵抗以及由此引起的高胰岛素血症。由于诊断标准的不同使得在不同人群中的发病统计率介于1％～8％之间。目前PCOS的发病原因尚未明确．以往的研究发现PCOS呈明冠的家族聚集现象，遗传因素可能起着相当关键的作用。但由于PCOS与低生育能力相关．很难进行大规模的连锁分析，而且疾病表型存在争议，
作者 祁冰 侯丽辉 吴效科 杨琳 宋家欣
机构地区 黑龙江中医药大学
出处 《世界中西医结合杂志》 2008年第8期498-499,502,共3页 World Journal of Integrated Traditional and Western Medicine
基金 黑龙江省自然科学基金重点项目"基因芯片筛选治疗卵巢胰岛素抵抗中药的研究"(No.ZJY0606-01)
关键词 多囊卵巢综合征 基因 激素
分类号 R711.75 [医药卫生—妇产科学]
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参考文献19

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共引文献24

同被引文献16

  • 1李桢,储明星,曹红鹤,李宏滨,马月辉,郑友民,周忠孝.中外11个猪种A-FABP基因微卫星遗传变异的研究[J].遗传,2004,26(4):473-477. 被引量：17
  • 2胡振兴,乔杰,李美芝,张小为,陈咏健,李蓉,孙春玲.多囊卵巢综合征相关基因的差异表达研究[J].北京大学学报（医学版）,2004,36(6):600-604. 被引量：25
  • 3胡卫红,乔杰,李蓉,王丽娜.多囊卵巢综合征患者血清脂肪型脂肪酸结合蛋白水平与性激素及血脂的相关性研究[J].中华医学杂志,2006,86(45):3186-3189. 被引量：9
  • 4邓新宇,姜颖,贺福初.磷酸化蛋白质及多肽相关研究的技术进展[J].遗传,2007,29(10):1163-1166. 被引量：12
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引证文献1

世界中西医结合杂志
2008年 第8期

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