MMPs、uPA与非何杰金淋巴瘤侵袭转移关系的研究进展
摘要
非何杰金淋巴瘤是一种侵袭性强、预后差的肿瘤,如何抑制肿瘤细胞的侵袭转移是当前重要的研究课题。基质金属蛋白酶和尿激酶型纤溶酶原激活物在胃癌、肠癌和肺癌等实体器官肿瘤中的促进侵袭作用已被较多的研究证实,但在淋巴造血系统肿瘤中的作用仍缺乏相关的研究。部分类型非何杰金淋巴瘤的侵袭依赖于基质金属蛋白酶的参与,而尿激酶型纤溶酶原激活物具备一定的调节基质金属蛋白酶活性的能力。针对两者的研究可能为将来的肿瘤治疗提供有利的理论依据。
出处
《牡丹江医学院学报》
2008年第5期55-56,共2页
Journal of Mudanjiang Medical University
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