口腔颌面部血管瘤的临床生物学行为与治疗策略

Clinical biological behavior and treatment strategy of hemangioma in oral and maxillofacial region

血管瘤目前尚无有效预防方法,通过对口腔颌面部血管瘤临床生物学行为的深入考察、分析,认为要取得最佳的治疗效果,需要在早期(增生初期)及时发现、明确诊断,有针对性地进行治疗。血管瘤存在2个快速生长期,其发生以及持续的时间是明确的。虽然口腔颌面部血管瘤治疗策略的选择仍存在争议,但治疗的关键还是早期进行干预,尤其是第1个快速生长期,是控制血管瘤的最佳时机和不可丧失的关键期,应采取积极措施,使血管瘤的增生受限和停止,而不进入第2个快速生长期。对病情和所处病期的明确诊断以及对病程的确切预期是选择治疗方案的基础,可以采用激光、硬化剂注射、口服激素等治疗手段,有效控制或治愈血管瘤。本文着重对激光、硬化剂注射治疗的方案进行讨论,认为周密的计划和精确的操作是治疗成功的关键。

Hemangioma can not be prevented until nowadays. Early identification and definite diagnosis are necessary to achieve the best outcome. The clinical biological behaviors of hemangiomas in oral and maxillofacial region are completely investigated and deeply analyzed in this paper. There are two distinct phrase of rapid proliferation of hemangioma, with explicit onset and lasting time. Although there is still controversy over the treatment modality of hemangiomas in oral and maxillofacial region, the only way to success is to treat the lesions in early stage, in particular, the first rapid proliferation phrase is the best opportunity and strategic point to control the growth of hemangioma or even cure the disease. Upon definite diagnosis, laser therapy, sclerotherapy and oral steroids are among the treatment options. The protocol of laser therapy and sclerotherapy is addressed in this paper. Careful planning and appropriate manipulation are the key components to the management of hemangioma in oral and maxillofacial region.