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耐甲氧西林金黄色葡萄球菌SCCmec遗传元件的分子结构与分型 被引量：1

Typing and genetic characteristics of staphylococcal cassette chromosome mec element of methicillin-resistant Staphylococcus aureus
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摘要 耐甲氧西林金黄色葡萄球菌（MRSA）是医院和社区感染的重要致病菌。SCCmec遗传元件不仅与MRSA的耐药产生密切相关，而且是MRSA感染株分型的重要指标。此文对MRSA中SCCmec遗传元件的结构特点、命名原则及分型方法等方面的研究进展作了综述。 Methicillin-resistant Staphylococcus aureus （MRSA） is an important pathogenic organism for both hospital and community infections. Staphylococcal cassette chromosome mec （SCC mec ） is correlated with the resistance of MRSA against β-lactams. It is also a key marker of typing for MRSA strains. The progress of genetic characteristics, nomenclature and typing of SCCmec are reviewed in this paper.
作者 祁伟
机构地区 天津医科大学第二医院感染性疾病研究所
出处 《国际流行病学传染病学杂志》 CAS 2008年第5期343-345,共3页 International Journal of Epidemiology and Infectious Disease
基金 天津市应用基础及前沿科技研究计划（08JCYBJC04300）
关键词 甲氧西林 葡萄球菌 金黄色 SCCmec遗传元件 Methicillin Staphylococus aureus SCCmec element
分类号 R446.5 [医药卫生—诊断学]
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参考文献17

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同被引文献47

  • 1ho T, Katayama Y, Hiramatsu K. Cloning and nucleotide sequence determination of the entire mec DNA of pre-methicillin-resistant Staphylococcus aureus N315 [ J]. Antimicrob Agents Chemother, 1999, 43(6) : 1449-1458.
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  • 6Kwon NH, Park KT, Moon JS, et al. Staphylococcal cassette chro- mosome mec(SCCmec) characterization and molecular analysis for methicillin-resistant Staphylococcus aureus and novel SCCmec sub- type IVg isolated from bovine milk in Korea[ J]. J Antimicrob Che- mother, 2005, 56(4): 624-632.
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  • 10Ito T, Ma XX, Takeuchi F, et al. Novel type V staphylococcal cassette chromosome mec driven by a novel cassette chromosome recombinase, ccrC[J]. Antimicrob Agents Chemother, 2004, 48 (7) : 2637-2651.

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国际流行病学传染病学杂志
2008年 第5期

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