隔物灸对寒湿凝滞型原发性痛经患者经期血浆β-EP含量的影响

Effects of substance-partitioned moxibustion on plasma β-EP content in the patient with primary dysmenorrhea of cold-damp stagnation type in the menstrual period

目的:探讨隔物灸治疗寒湿凝滞型原发性痛经的作用机制。方法:以隔物灸治疗寒湿凝滞型原发性痛经患者105例(隔物灸组),并设中药月月舒作对照104例(药物组),观察临床疗效,同时对两组各40例进行了治疗前后经期β-内啡肽(β-EP)含量的变化检测。结果:隔物灸组总有效率为95.2%,优于药物组的85.6%(P<0.05);隔物灸组β-EP水平较治疗前明显升高(P<0.01)。结论:隔物灸对寒湿凝滞型原发性痛经患者有明显的治疗作用,其作用机制之一可能是通过调节血浆中β-EP的水平而发挥止痛效应。

Objective To probe into the mechanism of substance-partitioned moxibustion in treatment of primary dysmenorrhea （PD） of cold-damp stagnation type. Methods The treatment group （105 cases of PD） were treated with substance-partitioned moxibustion and the control group （104 cases） were treated with Chinese drug Yueyueshu. Their therapeutic effects were observed. Plasma β-endorphin contents in menstrual period were determined before and after treatment in 40 patients of each group. Results The total effective rate of 95.2% in the substance-partitioned moxibustion group was better than 85.6% in the control group （P〈0.05）; after treatment, plasma β-endorphin content significantly increased in the substance-partitioned moxibustion group （P〈0.01）. Conclusion Substance-partitioned moxibustion has obvious therapeutic effect on primary dysmenorrhea of cold-damp stagnation type, which is carried out possibly through regulating the plasma β-endorphin content as one of the mechanisms.