针药复合麻醉肺癌手术下SOD水平的变化

Clinical Study of a Change in SOD Level during Lung Cancer Surgery under Combined Acupuncture and Medicine Anesthesia

目的观察针刺对肺癌手术患者SOD水平的调节,从中观察其对于红细胞免疫的影响。方法采用超氧化物歧化酶测试盒检测肺癌患者血清中SOD含量;将针药麻组与全麻组肺癌手术患者各30例分别在入院、术前一天、术后第7天、术后第11天测量SOD含量作比较,其中针药麻组术前3天,术中及术后6天,针刺大椎、命门、足三里、三阴交穴。结果血清中SOD含量在入院和术后第11天作两组比较,差异无统计学意义(P>0.05);在术前一天与术后第7天作两组比较,差异有统计学意义(P<0.01),针药麻组优于全麻组。结论针刺能升高肺癌手术患者血清中SOD含量,对肺癌手术患者有调节免疫功能的作用。

Objective To observe the change in SOD level in patients receiving lung cancer surgery under acupuncture anesthesia and investigate the influence of acupuncture on erythrocytic immunity. Methods Serum superoxide dismutase （SOD） content was measured using SOD test kit in lung cancer patients. Patients who will receive lung cancer surgery were divided into two groups. SOD content was measured in the acupuncture-medicine anesthesia group of 30 cases and the general anesthesia group of 30 cases at admission, one day before and seven days after surgery. The contents were compared. The acupuncture-medicine anesthesia group were acupunctured at points Dazhu （ BL 11 ） , Mingmen （ GV 4）, Zusanli （ ST 36） and Sanyinjiao （ SP 6） at three days before, during and six days after surgery. Results A comparison of SOD contents between the two groups showed no statistically significant difference at admission and eleven days after surgery （ P 〉 0.05 ）, but there was a statistically significant difference between the two groups at one day before and seven days after surgery （P 〈 0.05 ）. It was significantly better in the acupuncture-medicine anesthesia group than in the general anesthesia group. Conclusion The results indicate acupuncture can increase SOD content and produce a regulating effect on immune function in lung cancer surgery patients.