摘要
目的:调查乳腺癌患者术后化疗的药物利用情况,比较不同方案的药物费用。方法:采用病例回顾分析方法,对105例接受术后化疗的乳腺癌患者药物治疗方案、药物利用情况和药物不良反应进行统计分析。结果:105例患者共使用了5类共17种不同的化疗方案,平均单周期化疗药物费用7445.34元、辅助治疗药物费用2899.53元、药物总费用10344.87元,其中以CEF方案(环磷酰胺+表阿霉素+氟尿嘧啶)药物费用最低。结论:影响药物费用的主要因素是化疗方案、辅助治疗药物和药品生产厂家的选择,临床在制定化疗方案时仍有待于进一步规范。
OBJECTIVE ： To investigate the utilization of antineoplastic drugs in post - mastectomy breast cancer patients and compare drug fees between different chemotherapy schedules. METHODS： The chemotherapy schedule, drug utilization and adverse drug reactions in 105 post - mastectomy breast cancer patients were statistically analyzed in a retrospective study. RESULTS： There were 5 types （17 kinds） of chemotherapy schedules used in the 105 cases. The total drug cost were 10 344.87 Yuan on average in a single treatment cycle, including antineoplastic drug fee （7 445.34 Yuan） and cost of adjuvant drugs （2 899.53 Yuan）. The CEF schedule （CTX ＋ EADR ＋ 5 - FU） was the cheapest one in all the 17 kinds of schedules. CONCLUSION： The main factors which influenced drug fees were the selection of chemotherapy schedule, using of adjuvant therapeutic drugs and the selection of drug manufacturers. The choice of chemotherapy remains to be standardized further.
出处
《中国医院用药评价与分析》
2008年第10期736-737,共2页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
乳腺癌
化疗
药物利用
Breast cancer
Chemotherapy
Drug utilization
