益生菌和肠易激综合征的关系

Relationship between probiotics and irritable bowel syndrome

肠易激综合征(IBS)是最常见的功能性胃肠病之一,其发病机制目前还不明确。近年发现肠道微生物群可能参与了IBS的发生发展,细菌感染可以诱发感染后IBS;有一部分IBS患者存在小肠细菌过度生长(SIBO)或是菌群组成改变;口服肠道不吸收的抗生素能够减轻IBS的症状。因此有人提出用益生菌治疗IBS可能是一个合理的方法。此文就益生菌治疗IBS的相关研究作一综述。

Irritable bowel syndrome is one of the most common functional gastrointestinal disorders,of which the pathogenesis is not yet clear. Recently, the effects of intestinal microflora get more and more attention in the pathogenesis of irritable bowel syndrome. Epidemiological proof and clinical proof indicate that the infection of gastrointestinal can induce post infectious irritable bowel syndrome, some patients exist small intestinal bacteria overgrowth and dysregulation of intestinal bacteria,antibiotic can relive the symptoms of some patients with irritable bowel syndrome. So someone consider that using probiotics may be a beneficial and reasonable method for the patients of irritable bowel syndrome.