摘要
功能性胃肠病(FGID)有一定程度的家族聚集现象,在孪生人群中的FGID流行病学研究显示,单卵孪生的共同患病率高于异卵孪生。这些现象提示,遗传因素改变个体对FGID的易感性以及相似环境致病因素下FGID的临床表现异质性。此文综述FGID遗传易感性方面的研究进展。
The clustering of FGID（Functional gastrointestinal disorders） in families has been observed. In the epidemiologic study of FGID in the group of twin pairs, it has been found that the concordance rate for FGID is higher in monozygotic twin pairs than in dizygotic twin pairs. It reveals that genetic factors alter the individual＇s susceptibility to FGID and determine the heterogeneity of clinical manifestations which are exposed to similar environmental factors. We review latest advancement of studies of the genetic susceptibility of FGID.
出处
《国际消化病杂志》
CAS
2008年第5期377-379,共3页
International Journal of Digestive Diseases
关键词
功能性胃肠病
遗传因素
肠易激综合征
Functional gastrointestinal disorders
Genetic factors
Irritable bowel syndrome
