909例孕妇50g葡萄糖筛查试验结果分析

The analysis of 50g glucose challenge screening test result in 909 cases of pregnant women

目的探讨50g葡萄糖负荷试验(50g GCT)对妊娠期糖尿病(GDM)的检出意义。方法选择2005年6月至2008年3月在我院行产前检查并接受50g GCT的孕妇909例,对筛查结果阳性(即血糖值≥7.8mmol/L)的224例再行75g葡萄糖耐量试验(OGTT)。结果①909例中有224例50g GCT筛查阳性,诊断GDM 56例,GIGT 80例。②高龄、肥胖和糖尿病家族史是GDM的高危因素。③GDM孕妇巨大儿、早产的发生率和剖宫产率均显著高于健康孕妇。结论GDM母儿并发症多,50g GCT对GDM的及时发现和治疗具有重要意义,高龄、肥胖和糖尿病家族史是GDM的高危因素,具有高危因素的孕妇更应及早筛查。

Objective To investigate the value of 50g glucose challenge test （50gGCT） in screening gestational diabetes mellitus （GDM）. Methods Among the 909 gestational pregnant women who were having prenatal check from June 2005 to March 2008, 224 cases had positive screening result and they were given a 75g OGTT. Results 1. Total of 909 women were screened with 224 having a positive screening value. Of them, 80 women have a subsequent GIGT and 56 women were diagnosed as GDM. 2. Age, obesity and the family history of GDM are the high risk factors of GDM. 3. The probability of giant baby and premature delivery, as well as the rate of cesarean section delivery of GDM was higher than the normal pregnant women. Conclusion 50g GCT is of vital importance to the early - stage diagnosis and further treatment of GDM. Age, obesity and the family history are the high risk factors of GDM. Pregnant woman who has high risk factors of GDM should have prenatal check the earlier the better.