急性胰腺炎CT灌注成像

Perfusion imaging of human acute pancreatitis using dynamic computed tomography

目的:探讨急性胰腺炎CT灌注成像特征。方法:采用40层螺旋CT对60例患者进行胰腺CT灌注检查,其中包括30例正常对照者和30例急性胰腺炎病例。灌注成像原始数据经Siemens体部灌注软件测量,并对急性胰腺炎和正常胰腺的灌注参数进行比较。结果:急性胰腺炎组的血流量为(0.95±0.19)ml/(min.ml),低于正常组的(1.63±0.34)ml/(min.ml),血容量为(0.22±0.06)ml/ml,低于正常组的(0.26±0.04)ml/ml,通透性为(1.25±0.97)ml/(min.ml),高于正常组的(0.14±0.07)ml/(min.ml),差异有显著性(P<0.05)。常规CT增强与CT灌注成像检出率差异不显著。急性水肿型胰腺炎和急性出血坏死型胰腺炎灌注参数差异不显著。结论:急性胰腺炎血流灌注减低,通透性升高。CT灌注成像有利于早期辅助诊断急性胰腺炎。

Objective： To describe CT perfusion imaging in patients with acute pancreatitis. Methods： CT perfusion imaging was performed in 60 patients including 30 healthy subjects without pancreatic diseases. The raw data was calculated by Siemens perfusion CT （PCT） and the perfusion values were compared, Results： Blood flow in patients with pancreatitis was （0.95±0.19）ml/（min·ml）, in control was （1.63±0.34）ml/（min·ml）, Blood volume in patients with pancreatitis was（0.22±0.06）ml/ml, in control was （0.26±0.04）ml/ml. Permeability in patients with pancreatitis was （1.25±0.97）ml/（min·ml）, in control was （0.14± 0.07）ml/（min·ml）（P〈0.05）. There was no significance between contrast CT and PCT. Conclusion： Perfusion was reduced and permeability was improved in patients with panereatitis, The information afforded by CT perfusion imaging can help diagnosis of pancreatitis in the early stage,