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抗血小板药物的应用进展 被引量：2

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摘要 目前动脉血栓栓塞性疾病是人类重要的致死疾病之一，而血小板的激活、黏附、聚集、释放是动脉血栓启动的一个重要机制。多个有关抗血小板药物的大规模随机对照临床试验以及对此的荟萃分析目表明，在有血管阻塞性疾病患者中应用阿司匹林及其他抗血小板药物治疗可减少大约25％的严重动脉血栓栓塞事件。现通过对抗血小板药物的作用机制、有效性、不良反应及最佳剂量与最近有关的大规模临床试验的回顾，从而为临床动脉血栓栓塞性疾病的防治中抗血小板药物的应用提供帮助。
作者 卢风生 卢彩兰
机构地区 山西省运城市卫生学校附属医院急诊科 山西医科大学第二医院急诊科
出处 《中国医师进修杂志（内科版）》 2008年第9期65-67,共3页 Chinese Journal of Postgraduates of Medicine
关键词 抗血小板药物 随机对照临床试验 血栓栓塞性疾病 大规模临床试验 动脉血栓 血管阻塞性 致死疾病 荟萃分析
分类号 R973.2 [医药卫生—药品] R560.5 [医药卫生—呼吸系统]
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参考文献22

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同被引文献23

  • 1Schror K. New antiplatelet agents and the question of dual anti- platelet therapy. Internist ( Berl), 2012,53 ( 3 ) :351-356.
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  • 5Lopes RD. Antiplatelet agents in cardiovascular disease. J Thromb Thrombolysis, 2011,31 ( 3 ) :306-309.
  • 6Lischke S, Schneider DJ. Recent developments in the use of anti- platelet agents to prevent cardiovascular events. Future Cardiol, 2011,7(3) :403-413.
  • 7Kalyanasundaram A, Lincoff AM. Managing adverse effects and drug-drug interactions of antiplatelet agents. Nat Rev Cardiol, 2011,8(10) :592-600.
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  • 10Nonsteroidal anti-inflammatory drugs add an anti-ulcer drug for patients at high risk only. Always limit the dose and duration of treatment with NSAIDs[J].PRESCRIRE INTERNATIONAL,2011,(119):216-219.

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中国医师进修杂志（内科版）
2008年 第9期

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