农药微乳剂配方设计的方法研究

Study on Method of Pesticide Microemulsion Formulation Design

[目的]为提高农药微乳液的质量和性能提供科学的依据。[方法]从物质体系的相图为切入点,以物理化学和胶体界面的基本理论为依据,利用相图与正交试验相结合的方法,研究得到最佳农药微乳液配方的方法。[结果]根据相图中形成微乳液区域及可无限稀释区域的面积大小,找到每个因素的最佳水平,将几个因素的最佳水平结合起来,就组成了能形成最佳相图的各个组分的含量。然后在此基础上,详细地绘制在最佳组分含量情况下的拟三元相图,在相图的微乳液区域,依据生产实际,确定最终产品的配方。[结论]该研究为进一步提高我国在农药微乳液制剂方面的技术、提高农药微乳液的质量和性能以及该剂型在农业生产中的推广和普及打下了基础。

[Objective] The aim was to provide the scientific basis for improving the quality and performance of pesticide microemulsion. [Method] With the phase diagram of material system as breakthrough point and the basic theory of physical chemistry and colloid surface as the basis, the method of the optimum pesticide microemulsion formulation design was obtained by the method of phase diagram combined with orthogonal experiment. [ Result] The optimum level of every factor was found according to the forming area of microemulsion region in the phase diagram and the infinite diluted region. Combining the optimum level of these factors, the content of each component forming optimum phase diagram was constituted. Then on this basis, the pseudo - ternary phase diagram under the condition of optimum component content was protracted in detail. The formulation of the fmal production was determined in the microemulsian region of the phase diagram according to the actual production. [ Conclusion] The research laid the foundation for improving the technology of pesticide microemulsion in pharmaeeutics, improving the quality and performance of pesticide microemulsion and popularizing the formulation in agricultural production.