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非常严格控制2型糖尿病血糖是否安全——目标是糖化血红蛋白小于6.5%,但不使用高强度治疗方案

Safety of very tight blood glucose control in type 2 diabetes --Aim for glycated haemoglobin lower than 6.5%, but without using highly intensive treatment
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摘要 2008年2月8日,在高危心血管事件发生风险的2型糖尿病患者进行的一项大型随机对照研究(ACCORD),因为安全性问题被提前18个月终止了。高强度降低血糖以期达到较现有指南推荐的目标值更低的治疗目标(糖化血红蛋白(HbAlc)〈6.0%),与降糖力度稍低的标准治疗方案(HbAlc7.0%-7.9%)相比,增加了死亡的风险。这在控制率是10/1000/受试者年的基础上,增加额外死亡3/1000/受试者年。
出处 《英国医学杂志中文版》 2008年第5期262-263,共2页 The BMJ Chinese Edition
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参考文献11

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