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双相波体外除颤器对室颤幼猪除颤效果的试验研究 被引量：1

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摘要 目的遵循《指南2005》以50J-70J-70J能量的双相波对室颤幼猪进行点击除颤,研究其除颤效果。方法太湖猪经5mA电流诱导室颤后,50J的能量进行除颤后立即CPR(心肺复苏术),不能成功复律者能量增加至70J并继续CPR,计算成功率,心电监护、多普勒超声及血液分析测定心功能及心肌酶谱。结果一次除颤成功率达100%,射血分数(EF)、左心室面积变化率(FAC)4h内均显著降低(P<0.05),K+在除颤成功4h内显著升高(P<0.05),72h后恢复正常,而BE在成功后3、4h明显降低(P<0.05),72h巨检未件异常。结论以50J-70J-70J能量电击加CPR的方案可有效的对室颤幼猪进行除颤,且无不可逆性损伤,是切实可行的。
作者 周正宇 王禹斌 周慧英 黄猛 刘慧婷 殷音 顾静 薛智谋
机构地区 苏州大学实验动物中心
出处 《实验动物与比较医学》 CAS 2008年第5期338-340,348,共4页 Laboratory Animal and Comparative Medicine
关键词 固定能量 双相波 猪 除颤
分类号 R541.7 [医药卫生—心血管疾病]
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参考文献9

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二级参考文献12

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实验动物与比较医学
2008年 第5期

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