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哺乳动物雷帕霉素靶蛋白靶标及其靶向治疗 被引量：1

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摘要 哺乳动物雷帕霉素靶蛋白(mTOR)是细胞生长过程中极为重要的靶标,可被多种生长因子和细胞因子激活。mTOR的活性改变及表达异常可诱发多种疾病,如肿瘤、血管增殖性疾病、代谢综合征等。针对mTOR靶标,采用靶向技术干预,可望治疗上述疾病。
作者 郑炜 史道华
机构地区 南京军区福州总医院药学科
出处 《医药导报》 CAS 2008年第11期1366-1369,共4页 Herald of Medicine
基金 南京军区医药卫生科研基金课题(基金编号:06MA154)
关键词 雷帕霉素靶蛋白 雷帕霉素 反义RNA RNA干扰 靶向治疗
分类号 R966 [医药卫生—药理学] R967 [医药卫生—药理学]
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参考文献28

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二级参考文献50

共引文献6

同被引文献24

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医药导报
2008年 第11期

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