凯时治疗肺栓塞继发肺动脉高压疗效观察

Curative effect Observation on Secondary Pulmonary Hypertension Caused by Pulmonary Embolism Treated with Kaishi

目的观察凯时注射液治疗肺栓塞继发肺动脉高压的疗效。方法48例肺栓塞继发肺动脉高压患者随机分为凯时治疗组(24例)和川芎嗪对照组(24例)。结果治疗组显效率(54.2%)明显高于对照组显效率(25%);治疗组有效率(87.2%)高于对照组有效率(58.3%)。治疗组肺动脉压平均降低0.71 kPa(5.32 mmHg),与对照组肺动脉压平均降0.20 kPa(1.52 mmHg),无显著差异(P>0.05)。结论虽未观察到凯时有明显降低肺动脉压作用,但对肺栓塞患者临床症状缓解有显著作用。

Objective To observe the curative effect of secondary pulmonary hypertension （SPH） caused by pulmonary embolism treated with Kaishi injection. Methods 48 cases of such patient were divided into control group 24 cases who were injected with Kaishi and other 24 cases were treated with as control group. Results qhe effective rate in therapy group was 87.2% which is higher than that in control group 58.3%. The improve rate in therapy group was 54.2% which is higher than that in control group 25 %. The PMAP decreased 0.71 kPa in therapy group and 0.20 in control group. Conclusion This drug might relief clinical symptom although it have no obviously decreasing pulmonary pressure.