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国产奎硫平与奋乃静治疗老年期精神分裂症对照研究 被引量:3

A clinical study on Quetiapine versus Perphenanize in treatment of senile schizophrenia
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摘要 目的:比较国产奎硫平与奋乃静对老年期精神分裂症的治疗效果及安全性。方法:以奎硫平与奋乃静对66例老年期精神分裂症进行为期8周的对照治疗,采用阳性和阴性症状量表评定疗效,用副反应量表评定不良反应。结果:两组疗效差异无显著性(P>0.05)。奎硫平不良反应显著少于奋乃静(P<0.01)。结论:奎硫平是一种安全有效的抗精神病药。 Objective: To compare the offieacy and safety of quetiapine and perphenanize in senile schizophrenia. Methods: Quetiapine and perphenanize to be used on 66 of senile schizophrenia for 8 weeks, PANSS and TESS were used to access the efficacy and side effects. Results: There was no significant difference in efficacy between two groups, quetsapine bad less effect than perphenanize. Conclusion: Quetsapine is a safe effective antipsy chotic drug.
出处 《中国民康医学》 2008年第20期2387-2388,共2页 Medical Journal of Chinese People’s Health
关键词 老年期精神分裂症 奎硫平 奋乃静 Senile Schizophrenia Quetiapine Perphenanize
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参考文献10

  • 1赵靖平,朱荣华.奎的平:一种新的非典型抗精神病药[J].国外医学(精神病学分册),2000,27(1):36-39. 被引量:274
  • 2Mc Convile B J, Arvanitis LA, Thyrum Pt. et al. Phyarma Cokinetics. Tolerability and clinical effectiveness with psychotic Disorders [J] .J Clin Psychiatry,200,61:252 - 260.
  • 3中华医学会精神科分会.中国精神障碍分类与诊断标准(CCMD-3)[M].第3版.济南:山东科技出版社,2001,75-78.
  • 4何燕玲,张明园.阳性和阴性综合征量表(PANSS)及其应用[J].临床精神医学杂志,1997,7(6):353-355. 被引量:477
  • 5张明园.精神科量表评定手册[M].长沙:湖南科学技术出版社,1998.17-27.
  • 6曹秋云,江开达.奎硫平国外资料介绍[J].临床精神医学杂志,2002,12(4):229-230. 被引量:164
  • 7陈晋东,赵靖平,李乐华,陈远光,陈晓岗,黄继忠,张鸿燕,周沫,谢世平,文启琴,张铁林,宫玉祥,秦英绂,范洪玉.国产奎硫平与氯丙嗪治疗精神分裂症的多中心双盲对照研究[J].中华精神科杂志,2001,34(4):193-196. 被引量:56
  • 8Marder SR, McQuade RD, stock E, et al. Aipipraxole in tile treatment of schizophrenia: Safely and tolerability in short - term placebo - cont rolled t rials [ J ]. Schizophr Res, 2003,61 (2 - 3) : 123.
  • 9Fabrf LF,Arvanitis L, Pultz J,et al.Seroquel,a novel,atypical antipsychotic: early indication of safety and efficacy in patients with chronic and subchronic schizophrenia [ J ]. Clin Therapeutics, 1995,17:366 - 378.
  • 10Hirsch SP, Link C GG, Goldstein J M, et al. Seroquel, a new atypical antipsychotic drug[ J ]. Br Psychiatry, 1996,29 (Suppl) : 45 - 46.

二级参考文献29

  • 1[1]Goldstein JM. Atypical antipsychotic drugs :beyond acute psychosis, new directions. Emerging Drugs, 1999,4:127
  • 2[2]Small JG, Hirsch SR, Arvanitis LA, et al. Quetiapine in patients with schizophrenia. A high- and low-dose double-blind comparison with placebo. Seroquel Study Group. Arch Gen Psychiatry,1997,54:549
  • 3[3]Borison RL, Arvanitis LA, Miller BG. ICI 204.636, an atypical antipsychotic: efficacy and safety in a multicenter, placebo-controlled trial in patients with schizophrenia. US Seroquel Study Group. J Clin Psychopharmacol, 1996,16:158
  • 4[4]Arvanitis LA,Miller BG and the Seroquel Trial 13 Group.Multiple fixed doses of "Seroquel"(quetiapine) in patients with acute exacerbation of schizophrenia:a comparison with haloperiadaol and placebo.Biol Psychiatry,1997,42:233
  • 5[5]Beasley CM,Sanger T,Satterlee W,et al.Olanzapine versus placebo:results of double-blind,fixed dose olanzapine trail.Psychopharmacology,1996,124:159
  • 6[6]Tran PV,Hamilton SH,Kuntz AJ,et al.Double-blind comparison of olanzapine versus risperidone in the treatment of schizophrenia and other psychotic disorders.J Clin Psychopharmacol,1997,17:407
  • 7[7]Kasper S,Muller-Spahn F.Review of quetiapine and its clinical applications in schizophrenia.Exp Opin Pharmacother,2000,1:783
  • 8[8]Purdon S,Malla A,Labelle A,et al.Neuropsychological change in patients with schizophrenia after treatment with quetiapine or haloperidol.J Psychiatr Neurosci,2001,26:137
  • 9[9]Hellwell J,Mckeller M,Raniwalla J."Seroquel":efficacy in aggression,hostility and low mood of schizophrenia [abstract].Presented at the CINP Congress,1998,Glasgow UK
  • 10[10]Tariot PH,Salzman MD,Yeung PP,et al.Long-term use of quetiapine in elderly patients with psychotic disorders.Clin Ther,2000,22:1068

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