尼莫地平治疗脑出血并破入脑室45例疗效观察

Curative Effects of Nimodipine on Hypertensive Intracerebral Hemorrhage with Secondary Ventricular Hemorrhage

目的观察尼莫地平治疗高血压性脑出血并破入脑室的疗效及副作用。方法设尼莫地平治疗组和常规治疗对照组,前者在常规治疗的同时于发病48 h内开始应用尼莫地平治疗。结果尼莫地平治疗组治疗高血压性脑出血并破入脑室总有效率82.2%,明显优于常规治疗的对照组(48.9%);尼莫地平治疗组病死率6.67%,明显低于常规治疗的对照组(22.2%);尼莫地平副作用发生率(4.4%)低且症状轻。结论尼莫地平治疗高血压性脑出血并破入脑室显著降低了该病的病死率及致残率,副作用少,临床应用经济、安全、疗效好。

Objective To evaluate the efficacy and side effect of Nimodipine on hypertensive intracerebral hemorrhage and secondary ventricular hemorrhage. Methods Patients with cerebral hemorrhage were randomly divided into Nimodipine treatment group and conventional control group. The treatment group was given Nimodipine injection in 48h on the basis of general therapy. Results The total effective rate of treating hypertensive intracerebral hemorrhage and secondary ventricular hemorrhage was 82.2% in Nimodipine treatment group and more effective than 48.9% in control group. The death rate was 6.67% in treatment group and much lower than 22.2% in control group. The rate of side effect is 4.4% and symptom is minimal. Conclusions Nimodipine can facilitate death rate, deformity rate and side effect of cerebral hemorrhage patients. It is cheap and has high safety and curative effect.