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晚期糖基化终末产物受体与肿瘤的关系 被引量：2

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摘要 晚期糖基化终末产物受体（receptor for advanced glycation end products,RAGE）是细胞表面分子免疫球蛋白超家族成员之一,属多配体受体,其通过与细胞表面不同配体结合发挥效应,广泛研究表明：RAGE参与糖脂代谢、细胞增殖与分化、炎症反应等生理病理过程。
作者 景蓉蓉 王惠民
机构地区 南通大学附属医院 南通大学检验系
出处 《实验与检验医学》 CAS 2008年第5期541-542,574,共3页 Experimental and Laboratory Medicine
关键词 糖基化终末产物受体 晚期 细胞表面分子 肿瘤 免疫球蛋白 家族成员 配体受体 配体结合
分类号 R589 [医药卫生—内分泌] R53 [医药卫生—内科学]
  • 相关文献

参考文献16

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  • 3[3]Schmidt AM,Yan SD,Yan SF,et al.The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses[J].J Clin Invest,2001,108(7):949～955.
  • 4[4]Hudson BI,Carter AM,Harja E,et al.Identification,classification,and expression of RAGE gene splice variants[J].FASEB J,2008,22(5):1572～1580.
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  • 7景蓉蓉,王惠民,鞠少卿,祝文彩,张志泉.实时荧光定量PCR检测RAGE mRNA方法的建立及初步应用[J].临床检验杂志,2008,26(1):55-58. 被引量：2
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二级参考文献8

  • 1王燕,闻新棉,窦恒利,仲人前.自身免疫病患者增殖诱导配体基因mRNA表达水平的研究[J].临床检验杂志,2006,24(4):299-301. 被引量：3
  • 2Schmidt A M, Yan S D, Yan S F, et al. The biology of the receptor for advanced glycation end products and its ligands[ J]. Biochim Biophys Acta,2000,1498 ( 2-3 ) :99-111.
  • 3Kuniyasu H, Chihara Y, Takahashi T. Co-expression of receptor for advanced glycation end products and the ligand amphoterin associates closely with metastasis of colorectal cancer [ J ]. Oncol Rep,2003,10 (2) :445-448.
  • 4Sasahira T, Kirita T, Bhawal U K, et al. The expression of receptor for advanced glycation end products is associated with angiogenesis in human oral squamous cell carcinoma [ J ]. Virchows Arch, 2007,450 (3) :287-295.
  • 5Takeuchi A, Yamamoto Y, Tsuneyama K, et al. Endogenous secretory receptor for advanced glycation endproducts as a novel prognostic marker in chondrosarcoma [J]. Cancer,2007,109 ( 12 ) :2532-2540.
  • 6Lizotte P P, Hanford L E, Enghild J J, et al. Developmental expression of the receptor for advanced glycation end-products (RAGE) and its response to hyperoxia in the neonatal rat lung [ J ]. BMC Dev Biol, 2007,7 : 15.
  • 7Battling B, Hofmann H S, Weigle B, et al. Down-regulation of the receptor for advanced glycation end-products ( RAGE ) supports nonsmall cell lung carcinoma [ J ]. Carcinogenesis, 2005,26 ( 2 ): 293- 301.
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共引文献1

同被引文献46

  • 1王瑞良,苏青.RAGE及其配体的临床意义研究进展[J].国际内分泌代谢杂志,2006,26(3):160-162. 被引量：23
  • 2慢性阻塞性肺疾病诊治指南(2007年修订版)[J].中华结核和呼吸杂志,2007,30(1):8-17. 被引量：8230
  • 3Ramasamy R, Vannucci SJ, Yan SS, et al. Advanced glycation end - products and RAGE. a common thread in aging, diabetes, neurodegen- eration, and inflammation [J]. Glycobiology, 2005, 15 (7): 16R -28R.
  • 4Yan SF, Ramasamy R, Sehmidt AM. Mechanisms of disease: ad- vanced glycation end - products and their receptor in inflammation and diabetes complications : J ]. Nat Clin Pract Endocrinol Metab, 2008,4 (5): 285-293.
  • 5Zhong N, Wang C, Yao W, et al. Prevalence of chronic obstructive pulmonary disease in China : a large, population - based survey [ J ]. Am J Respir Crit Care Med, 2007, 176 (8) : 753 -760.
  • 6van Zoelen MA, Achouiti A, van der Poll T. The role of receptor for advanced glycation endproducts (RAGE) in infection [ J ]. Crit Care, 2011, 15 (2): 208.
  • 7Friggeri A, Banerjee S, Biswas S, et al. Participation of the receptor for advanced glycation end products in efferocytosis [ J]. J Immunol, 2011, 186 (11): 619l-6198.
  • 8Kikkawa T, Sato N, Kojika M, et al. Significance of measuring SIOOA12 and sRAGE in the serum of sepsis patients with postoperative acute lung injury [J]. Dig Surg, 2010, 27 (4) : 307 -312.
  • 9Buckley ST, Ehrhardt C. The receptor for advanced glyeation end prod- ucts (RAGE) and the lung [ J ]. J Biomed Biotechnol, 2010 (2010) : 917108.
  • 10Kim JK, Park S, Lee M J, et al. Plasma levels of soluble receptor for advanced glycation end products (sRAGE) and proinflammatory ligand for RAGE ( EN - RAGE) are associated with carotid atherosclerosis in patients with peritoneal dialysis [J:. Atherosclerosis, 2012, 220 (1) : 208 -214.

二级引证文献12

实验与检验医学
2008年 第5期

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