黄芪胶囊缓解体力疲劳作用实验研究

Experimental observation on the effect of Astragalus capsules in alleviating physical fatigue.

目的探讨黄芪胶囊对小鼠缓解体力疲劳作用。方法以小鼠为实验对象,用黄芪胶囊134.0mg/kg、268.0mg/kg、534.0mg/kg·BW分别给昆明种小鼠连续灌胃30d,进行小鼠负重游泳、血清尿素、肝糖原含量及血乳酸曲线下面积等指示测定,观察黄芪胶囊的抗疲劳功效。结果3个剂量组与阴性对照组比较,均能明显延长小鼠负重游泳时间,减少疲劳小鼠尿素的产生,降低血液中尿素水平,减少小鼠运动后血乳酸曲线面积,提高小鼠肝糖原的含量(P<0.01)。结论黄芪胶囊具有增强机体运动负荷适应能力,对抵抗疲劳和消除疲劳等也具有明显功能。

Objective To observe the effect of Astragalus capsules in alleviating physical fatigue. Methods The mice were fed with Astragalus capsule at the dosage of 134,268 and 534mg/kg. bw, respectively, once a day for 30 days. Then let the mice swim in load, the function of Astragalus capsules in alleviating physical fatigue was analyzed by determining the mensuration of the swimming time, serum urea, the level of Liver glycogen and blood lactic acid. Results The swimming time of mice in experimental group was longer than that of the control group. The levels of urea and lactic acid of tired mice after swimming in the experimental group were lower than those of controls. The recovery rate of lactic acid in experimental was more faster than that of control. In addiction the level of liver glycogen increase significantly in experimental group as compared with the control （ P 〈 0.01 ）. Conclusion It is suggested that Astragalus capsule can not only enhance the capability of adaptation to heavy exercise, but also have significant effect on prevention and elimination of lysis fatigue effect in physical strength after exercise.