杭州地区儿童肺炎支原体感染分析

Clinical observation of the characteristics in the children with respiratory infection in Hangzhou

目的调查杭州地区呼吸道感染儿童肺炎支原体（MP）感染情况和流行特点，为临床治疗和防止其爆发流行提供依据。方法随机采集在本院就诊并有呼吸道感染患儿的咽拭子，用FQ-PCR测定标本中MPDNA含量，若结果〉125拷贝为阳性，〈25拷贝为阴性。用统计学软件SPSS10．0分析MP感染和各调查因素之间的关系。结果在1502例呼吸道感染患儿标本中共检出391例MP阳性，阳性率占26．0％（391／1502）。感染机会、性别差异无显著性。7～15岁的儿童更容易感染，感染率占48．0％-62．1％。一年之中以夏秋季感染率最高，其中7月份高达37．3％。结论杭州地区MP引起儿童呼吸道感染的流行特点和南方其他地区的报道基本一致。

Objective To reveal the characteristics in the children with respiratory infection caused by Mycoplasma pneumoniae, and offer the evidences for clinical adminstration and prevention of it＇s outbreak. Methods The pharynx swabs were taken from the children with respiratory infection in our hospital. Fluorescence quantity polymerase chain reaction was used to determine the concentrations of Mycoplasma pnemnoniae＇s deoxyribonucleic acid. If the results were over or equal to 25copies,the samples were considered as positive. Otherwise,it would be considered as negative. The SPSS 10.0 software was used to analyse the relationships between infection opportunity and variable factors. Results The positive ratio in the 1502 eases with respiratory infection was 26.0 percent. There was no difference between infection opportunity and gender. The children aged from seven to fifteen years were more easier to be infected, with the infection ratios being 48.0 to 62.1 percent. The infection ratio was highest in summer,for example,37.3 percent in July. Conclusion The characteristics in the children with respiratory infection caused by Mycoplasma pneumoniae in Hangzhou were similar to those in other cities of southern area.