菝葜的化学成分研究

Studies on chemical constituents of rhizomes of Smilax china

目的:对百合科菝葜属植物菝葜Smilaxchina干燥的根茎进行化学成分研究。方法:采用硅胶、凝胶色谱法进行分离纯化,并运用现代波谱技术(ESI-MS,1H-NMR,13C-NMR)进行结构鉴定。结果:从菝葜的醋酸乙酯部分分离得到13个化合物,分别鉴定为:山柰酚-7-O-β-D-葡萄糖苷(1),黄杞苷(2),异黄杞苷(3),山柰酚(4),二氢山柰酚(5),二氢山柰酚-5-O-β-D-葡萄糖苷(6),芦丁(7),山柰酚-5-O-β-D-葡萄糖苷(8),白藜芦醇(9),香草酸(10),3,5-二甲氧基-4-O-β-D-吡喃葡萄糖基肉桂酸(11),β-谷甾醇(12),β-胡萝卜苷(13)。结论:化合物1,3,7,8,11为首次从该种植物中分离得到,化合物8,11为首次从该属中分离得到。

Objective ： To study the chemical constituents of the rhizomes of Smilax china. Method ： The constituents of the rhizomes of S. china were isolated and purified by repeated silica gel and Sephadex LH - 20 chromatography, and their structures were eluci- dated on the basis of spectral analysis. Result： Thirteen compounds were obtained and identified as kaemperol-7-O-β-D-glucopyranoside （ 1 ）, engeletin （2）, isoengeletin （3）, kaempferol （4）, dihydrokaempferol （5）, dihydrokaempferol-5-O-β-D-glucopyranoside （6）, rutin （7）, kaempferol-5-O-β-D-glucopyranoside （8）, 3, 5, 4＇-trihydroxystibene （9）, vanillic acid （10）, 3, 5-dimethoxy-4-O-β-D-glu- copyranosylcinnamic acid （11）, β-sitosterol （ 12）, and β-daucosterol （ 13）, respectively. Conclusion： Compounds 1, 3, 7, 8, and 11 were isolated from this plant for the first time, and compounds 8 and 11 were isolated from the genus Smilax for the first time.