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急性冠状动脉综合征患者血可溶性CD40配体的变化及意义

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摘要 目的探讨急性冠状动脉综合征患者血清可溶性CD40配体变化的临床意义。方法应用酶联免疫测定法对正常对照组40例、不稳定型心绞痛42例和急性心肌梗死13例的外周血可溶性CD40配体进行检测。结果急性冠状动脉综合征组血清可溶性CD40配体明显高于对照组(P<0.01),急性心肌梗死组血清可溶性CD40配体又高于不稳定型心绞痛组,差异有统计学意义(P<0.05)。随访期急性冠状动脉综合征组的可溶性CD40配体增高亚组心血管事件发生率明显高于正常组(P<0.01)。结论可溶性CD40配体升高可能与急性冠状动脉综合征的发生有关,是动脉粥样硬化斑块不稳定的标志。
出处 《岭南心血管病杂志》 2008年第5期356-357,共2页 South China Journal of Cardiovascular Diseases
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