超疏水纳米膜对变形链球菌在羟基磷灰石表面黏附的影响

Effects of superhydrophobic nanometer film on adhesion of Streptococcus mutans to hydroxyapatite ceramic surface

目的:探讨变形链球菌对表面涂有不同超疏水纳米膜的羟基磷灰石片的黏附和早期生物膜的形成。方法:比较涂有不同超疏水纳米膜和未涂有纳米膜的羟基磷灰石片对变形链球菌黏附的数量。采用体外黏附实验,了解变形链球菌在羟基磷灰石片上黏附量受表面超疏水纳米膜影响的状况。结果:3种涂有超疏水纳米膜(碳原子数量不同)的羟基磷灰石片;变形链球菌在其表面和未涂有纳米膜的羟基磷灰石片上黏附的细菌数量差异具有显著性。结论:在涂有含不同碳原子数目超疏水纳米膜的羟基磷灰石片上形成的生物膜和未涂有超疏水纳米膜的羟基磷灰石片表面形成的生物膜是不同的,且其上面黏附的细菌数量有所差别.提示超疏水纳米膜为口腔微态环境以及龋病和/或牙周病的发展具有重要意义。

Objective ：To examine the adhension on supcrhydrophobic nanometer film. Methods：The and formation of the dental biofilm by sreptococcus mutans adhension to the saliva--coated HA was decorated with superhydrophobic nanometer film by adhension experiment in vitro. Streptococcus mutans were compared with gengral hydroxyapatite ceramic. Results： The adhension of streptococcus mutans depended on the superhydrophobic nanometer film. The gengral materials had a higher bacterial accumulation,while there was a lower amount of bacterial accumulation on superhydrophobic nanometer film. Conclusion：The formed biofilms on hydroxyapatite ceramic decorated with or without superhydrophobic nanometer film differ,suggesting that superhydrophobic nanometer film plays an important role in the oral mieroenviroment and the development of caries and periodontal disease.