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代谢综合征病因及发病机制研究进展 被引量:16

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摘要 代谢综合征(metaboli esyndrome.MS)是一种以多种心血管危险因素聚集为特征的临床综合征。Reaven在1988年首先提出了MS的概念,最初的描述是包括高血压、肥胖、脂质代谢异常和胰岛素抵抗(IR.高胰岛素血症、空腹血糖升高和糖耐量异常),并指出IR是MS最重要的病理生理改变.是引起MS中其他异常改变的基础。随着人们生活水平的提高,MS的发病率日渐增高。MS是环境与遗传共同导致的复杂疾病。有关于其分子生物学研究是近期研究的热点之一。本篇就近几年来研究较多的与MS有关的病因及其发病机制综述如下。
作者 姚春莉 刘媛
出处 《实用医学杂志》 CAS 2008年第20期3453-3454,共2页 The Journal of Practical Medicine
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