静脉推注硫酸镁治疗毛细支气管炎合并心力衰竭疗效观察

A Study on the Clinical Effects of Vein Push of Magnesium Sulfate on the Capillary Bronchitis with Heart Failure

目的观察毛细支气管炎合并心力衰竭患儿采用静脉推注硫酸镁治疗的疗效。方法将毛细支气管炎合并心力衰竭用综合治疗效果不理想患儿,随机分为两组,对照组(26例)采用综合治疗;治疗组(26例)在综合治疗基础上采用25%硫酸镁溶液25mg/kg、加入5%葡萄糖溶液20mL,用输液泵静脉推注30min,1次/日。结果对照组13例(13/26),占50%,治疗组22例(22/26),占84.6%,两组比较总治愈率显著提高,差异显著(P<0.01);同时,治疗组在咳喘缓解、哮鸣消失、心率恢复正常、住院天数减少等方面均明显优于对照组,差异显著(P<0.01)。结论毛细支气管炎合并心力衰竭在综合治疗的基础上加用硫酸镁治疗,疗效明显,值得在基层医院推广应用。

Objective To observe the clinical effects of vein push of magnesium sulfate on the capillary bronchitis with heart failure. Methods 56 cases,treated with synthetic therapy and having the unideal therapy effect, diagnosed capillary bronchitis with heart failure,were divides into two groups randomly. 26 cases in the control group were treated with synthetic therapy. 26 cases in the treatment group were assist-treated with vein push of 25% magnesium sulfate （25mg/kg） plus 5% glucose 2Oral on the same synthetic therapy with the transfer pump in 30 minutes,1/day. Results The cure rates of the group with magnesium sulfat （22 cases, 22/26,84.6% ）showed a rapid improvement compared with those in the other group （13 cases,13/26,50% ）, their difference is remarkable（P〈 0.01 ）. The respiratory symptoms （such as wheezing, cough） and hospital days also improved obviously in the treatment group. Conclusion The clinical effects of magnesium sulfate on capillary bronchitis with heart failure on the synthetic therapy is evidence and the treatment is worth promoting application in the basic hospital.