摘要
目的从脱色剂的脱色机制及应用角度对近年来的脱色剂研究新进展进行综述。方法以生物及天然来源的化学脱色剂中常用的脱色剂为例介绍了两大类型脱色剂的脱色机制和应用。结果这些脱色剂都能抑制黑色素合成,均为临床可选药物,但有待进一步临床试验以评价它们的安全性。结论为各种脱色剂或增白剂制定安全的使用标准提供依据。
OBJECTIVE The review reveals the mechanism and clinical application of depigmenting agents which have been published recently. METHODS Taking the depigmenting agents usually used which are derived from biological and natural chemical depigmenting agents for example, the mechanism and clinical application of two kinds of depigmenting agents were introduced. RESULTS These depigmenting agents can inhibit synthesis of melanin, therefore, can be used clinically, however, further clinical experiment is needed to assess their security. CONCLUSION It can be provided to assess their safety and efficacy as the criterion.
出处
《中国现代应用药学》
CAS
CSCD
北大核心
2008年第5期397-400,共4页
Chinese Journal of Modern Applied Pharmacy
基金
“十一五”国家科技支撑计划课题(No.2006BAK10B09)
关键词
脱色剂
酪氨酸酶
黑色素
depigmenting agent
tyrosinase
melanin
