摘要
目的探讨血管内超声(IVUS)对于药物洗脱支架(DES)植入的影响。方法251例植入DES的患者随机分为两组,在冠状动脉造影(CAG)指导下植入的146例为Ⅰ组,在IVUS指导下植入的115例为Ⅱ组,对比两组支架植入的效果。结果在达到CAG支架植入理想情况下,Ⅱ组仍有61枚支架(53.0%)不符合IVUS支架植入标准,需进一步高压后扩张,IVUS检查前后,支架最大扩张压力(14.27±1.14)atm vs(18.62±0.63)atm(P<0.01),支架对称指数(13.9±1.5)%vs(4.1±1.2)%(P<0.01),支架膨展指数(76.0±3.4)%vs(95.2±4.2)%(P<0.01);Ⅰ组支架长度短于Ⅱ组,(21.00±3.23)mm vs(25.00±4.17)mm(P<0.01)、支架直径小于Ⅱ组,(2.97±0.41)mm vs(3.45±0.32)mm(P<0.01),最大扩张压力Ⅰ组低于Ⅱ组,(14.23±1.25)atm vs(18.62±0.63)atm(P<0.01)。结论对于DES的植入,IVUS具有重要指导作用。
Objective To evaluate the role of intravascular ultrasound (IVUS) in drug-eluting stent (DES) implantation. Methods A total of 251 patients with DES were divided into two groups. In group Ⅰ ( n = 146),DES were implanted by coronary angiography(CAG) only; group 11 ( n : 115),IVUS was used to evaluate the lesions and the effects. Results In group Ⅱ ,61 DES(53.0%) were optimum by CAG,but did not achieve the criteria of IVUS, additional higher-pressure post-dilatation was necessary. After that,the difference in the highest dilation pressure(14.27± 1.14) atm vs (18.62±0.63) atm( P 〈0.01) ,the stent symmetric index (13.9±1.5) % vs (4. 1±1.2) %( P 〈0.01), the stent inflation index (76.0±3.4) 0/oo vs (95.2±4.2) %( P 〈0.01) were obvious. Between the two groups,there was obvious difference in stent diameter(2.97 ± 0.41) mm vs (3.45 ± 0.32) mm( P 〈0.01), stent-length (21.00 ± 3.23) mm vs (25.00±4.17) mm( P 〈0.01) ,and the highest pressure of dilatation (14. 234±1.25) atm vs (18. 62± 0.63) atm( P 〈0.01). Conclusion IVUS is valuble in guiding DES implantation.
出处
《临床荟萃》
CAS
北大核心
2008年第22期1615-1617,共3页
Clinical Focus
关键词
冠状动脉疾病
超声检查
介入性
支架
coronary disease
ultrasonography, interventional
stents