摘要
目的建立脉络宁胶囊的质量标准控制方法。方法采用TLC法对本品中的牛膝、石斛、金银花进行鉴别;采用HPLC法对本品中的肉桂酸进行含量测定。结果在TLC色谱图中可检出牛膝、石斛、金银花;肉桂酸在0.1124~0.562μg范围内呈良好的线性关系(r=0.9999),平均回收率为96.51%,RSD=0.60%。结论所建立的方法可靠、准确、专属性强,可有效控制脉络宁胶囊的质量。
OBJECTIVE To establish the quality standard of Mailuoning Capsules. METHODS The Achyranthes bidentata BL. , Dendrobium Lindl. ,Lonicera japonica Thunb. were identified by TLC;The content of cinnamic acid was determined by HPLC. RESULTS The spots in TLC were quite clear, the linear range of cinnamic acid was 0. 1124 - 0. 562μg ( r = 0. 9999),the average recovery was 96.51% with RSD 0. 60%( n =5). CONCLUSION The method was reliable,specifie and accurate,and can effectively control the quality of Mailuoning Capsules.
出处
《齐鲁药事》
2008年第10期601-603,共3页
qilu pharmaceutical affairs