有晶状体眼虹膜固定型人工晶状体植入矫正高度近视的临床研究

Clinical research of the implantation of phakic iris-fixated intraocular lens for high myopia

目的探讨有晶状体眼虹膜固定型人工晶状体植入矫正高度近视的有效性、安全性和可预测性。方法对屈光度为-8.25～-28.00D的32例(53眼)高度近视患者行有晶状体眼Verisyse人工晶状体植入术。手术前、后观察患者的视力、屈光度数、眼压、角膜内皮细胞计数及并发症,术后随访时间6个月。结果53眼均成功植入Verisyse人工晶状体。术后第6个月时,患者裸眼视力≥4.7者占100%,最佳矫正视力≥4.9者占84.9%,裸眼视力和最佳矫正视力均较术前明显提高,差异具有统计学意义;90.6%患者术后屈光度在预期的±1.0D之内;眼压、角膜内皮计数与术前相比,差异均无统计学意义(P>0.05)。手术无严重并发症发生。结论有晶状体眼虹膜固定型人工晶状体植入矫正高度近视具有较好的有效性、安全性和可预测性,无严重并发症发生,但其远期效果有待于进一步观察。

Objective To evaluate the efficacy, safety and predictability of the implantation of Verisyse phakic iris -fixated intraocular lens （PIOL） for the correction of high myopia. Methods In this prospective study, 32 cases （53 eyes） with -8.25 ～-28.00 diopters （D） of myopia were implanted with the Verisyse phakic intraocular lens. Preoperative and postoperative visual acuity, refrac- tion, intraocular pressure, corneal endothelium and operative complications were observed. Results All of 53 eyes were implanted successfully and have been followed up for 6 months. A postoperative uncorrected visual acuity （UCVA） of 0.5 or better was observed in 100% eyes, a best corrected visual acuity （BCVA） of 0.8 or better was observed in 84.9% eyes at 6 months, and they were all significantly better than that of preoperative values （P〈0.05）; 90.6% of eyes were within ±1.0 D of the desired refraction; there were no statistically significantly difference between preoperative and postoperative mean intraocular pressure, corneal endothelial density （P 〉 0.05）. No severe complications were observed. Conclusion Implan- tation of the Verisyse irisixated PIOL in phakic eyes to correct high myopia is effective, safe and predictable, no severe complication occurred, but long-time follow-up is still required.