红景天苷对失眠大鼠睡眠周期的影响

Effect of Salidroside on the sleep phase of insomnia rats

目的:观察红景天苷对失眠大鼠睡眠时相的影响。方法:在恒温、恒湿、自动光控和电磁屏蔽实验条件下,采用大鼠皮层脑电描记方法,观察了红景天苷对失眠大鼠睡眠时相的影响。结果:给予失眠大鼠红景天苷后,失眠大鼠觉醒时间明显减少,睡眠总时间延长,主要表现为延长慢波睡眠Ⅱ期(SWS2)和快动眼睡眠(REMS)。结论:红景天苷能延长失眠大鼠的SWS2和REMS,可使失眠大鼠睡眠时相各期与正常大鼠睡眠时相各期占的比例接近。

Objective：To observe the effect of the salidroside on the sleep phase of insomnia rats. Methods： Under the conditions of constant temperature,constant humidity,light automatically and electromagnetic shielding,the effect of the salidroside on the sleep phase of insomnia rats was observed with the method of the cortical EEG.Results：The results showed that salidroside can obviously decrease the duration of W and increase TST,primarily prolong SWS2 and REMS.Conclusion：Salidroside can prolong SWS2 and REMS of insomnian rats and regulate the sleep phase of insomnia rats near the normal rats.