摘要
目的探讨血清中乳酸脱氢酶(LDH)与β2微球蛋白(β2-MG)水平与非霍奇金淋巴瘤(NHL)的预后关系。方法分别采用速率法和免疫比浊法测定126例NHL患者血清LDH和β2-MG值。结果NHL患者血清LDH和β2-MG测定值正常组的2年、4年生存率、缓解率明显高于测定值升高组,差异有统计学意义(P<0.05及P<0.01);高度恶性组与中低度恶性组LDH和β2-MG测定值有显著性差异(P<0.05)。结论血清LDH和β2-MG水平可作为NHL患者分期、预后的辅助指标。
Objective To evaluate the clinical significance of the serum lactic dehydrogenate（LDH） and β2 - Microglobulin （ β2 - MG） measuring in NOn - Hodgkins Lymphoma（NHL） Patients. Methods The LDH and 132 - MG are collected from 126 NHL patients and measured by rate method and radioimmunoassay respectively. Results The 2 - year survial, 4 - year survial and alleviation rate of Patientsinnormat LDH and 132 - MG level group were obviously higher than those intevel increasing group. Difference is of significance （p 〈0.05 and p 〈0. 01 ）. The LDH and β2 -MG level had significant difference （p 〈 0. 05 ） between high grade group and intermediate grade gronps. Conclusion The level of LDH and β2 - MG can be taken as an auxiliary clinical indicator to classify the phaseand to predict the prognosis in NHL patients.
出处
《医学研究杂志》
2008年第10期91-92,共2页
Journal of Medical Research
关键词
非霍奇金淋巴瘤
乳酸脱氢酶
Β2微球蛋白
预后
Non - Hodgkins lymphoma
Lactic dehydrogenate
β2 - Microglobulin
Prognosis
