药物治疗异位妊娠124例临床观察

Conservative treatment of ectopic pregnancy：an analysis of 124 cases

目的观察药物治疗异位妊娠的方法、疗效及安全性。方法将确诊为异位妊娠且符合药物保守治疗指征的124例患者随机分为四组：A组：单用甲氨蝶呤；B组：单用米非司酮；C组：甲氨蝶呤联合米非司酮；D组：甲氨蝶呤联合米非司酮联合中药。结果治疗成功率A组80．65％、B组61．29％、C组87．10％、D组90．32％，D组与其他三组比较，差异有统计学意义（P〈0．05，P〈0．01）；不良反应各组间相比较差异无统计学意义（P〉0．05）。结论甲氨蝶呤、米非司酮联合中药治疗异位妊娠疗效高，不良反应少。

Objective To explore a best therapy regimen for conservative treatment of eetopic pregnancy. Methods Total of 124 cases of ectopic pregnancy underwent medicine therapy. They were divided into 4 groups ： A group with MTX only, B group with mifepristone only, C group with MTX and mifepristone combination, and D group with combined MTX, mifepristone and Traditional Chinese medicine （TCM）. Results The curative rate was 80. 65% ,61.29% ,87.10% and 90.32% in group A,group B ,group C ,and group D. The curative rate of group D is higher than other groups （ P 〈 0.05,P 〈 0.01 ）. Conclusion Combined MTX, mifepristone and TCM has better effect on ectopic pregnany and has less side effects.