急性呼吸道感染患者血清CRP、PA和IL-6的检测及临床价值

Clinical Value of Serum C-reactive Protein,Prealbumin and Interleukin-6 to Patients Suffering from Acute Respiratory Infection

目的:探讨血清C反应蛋白(CRP)、前白蛋白(PA)及白细胞介素-6(IL-6)在急性呼吸道感染性疾病中的诊断价值和临床意义。方法:检测56例急性呼吸道感染患者和30例健康对照者血清CRP、PA和IL-6的含量。结果:细菌感染组与健康对照组相比较,CRP及IL-6水平明显升高,PA则明显降低,组间差异有高度显著性(P<0.01)。病毒感染组与健康对照组相比较,血清CRP、PA及IL-6水平差异均无显著性(P>0.05)。细菌感染组治疗前、后CRP、PA和IL-6水平差异均有高度显著性(P<0.01)。结论:在急性呼吸道感染时,血清CRP、PA和IL-6的含量呈不同程度的变化有助于疾病的早期鉴别诊断,动态检测其变化对疗效判断有一定的临床价值。

Objective:To investigate the diagnostic value and clinical significance of C-reactive protein(CRP),prealbumin(PA)and interleukin-6(IL-6)for the patients suffering from acute respiratory infection.Method:To collect and examine the levels of serum CRP,PA and IL-6 from 56 patients,and in the same time there were 30 normal persons for the contrast.Results:The levels of CRP and IL-6 of bacteria infection group were significantly higher than those of virus infection group and normal group(P<0.01),but the level of PA was opposite(P<0.01).There was little different(P>0.05)between viral infection group and the control group.When comparing the level of CRP and PA before and after treatment,there were significant differences(P<0.01)between them.Conclusion:In the acute respiratory infections,the changes of CRP,PA and IL-6 levels can be used to diagnose diseases in the early time,and dynamic monitor of CRP,PA and IL-6 has a certain significance in clinical therapy.