耐甲氧西林血浆凝固酶阴性葡萄球菌的检测

DETECTION OF METHICILLIN-RESISTANT COAGULASE-NEGATIVE STAPHYLOCOCCI

从３０株血浆凝固酶阴性的葡萄球菌中分离１３株耐甲氧西林血浆凝固酶阴性葡萄球菌（Ｍｅｔｈｉｃｉｌｉｎ－ＲｅｓｉｓｔａｎｔＣｏａｇｕｌａｓｅ－ＮｅｇａｔｉｖｅＳｔａｐｈｙｌｏｃｏｃｃｉＭＲ－ＣＮＳ）。ＭＲ－ＣＮＳ占ＣＮＳ分离率的４３．３％（１３／３０）。３０株ＣＮＳ对万古霉素全部敏感，Ｏｘａｃｉｌｉｎ的ＭＩＣ值≥８μｇ／ｍｌ的菌株同时耐１５种抗生素的９—１３种，Ｏｘａｃｉｌｉｎ的ＭＩＣ值≤２μｇ／ｍｌ的菌种只对１—５种抗生素耐药。由于ＭＲ－ＣＮＳ的分离率高，而且具有复合耐药性，所以我们要高度重视ＭＲ－ＣＮＳ引起的感染。

13 Methicillin-Resistant Coagulase-Negative Staphylococci(MR-CNS)were identified from 30 Coagulase-Negative staphylococci.The detection rate of MR-CNS was 43.3%(13/30)in Coagulase-Negative staphylococci.All of 30 CNS were susceptible to Vancomycin.The strains of oxacillin≥8μg/ml were resistible to 9—13 of 15 antibitotics,the strains of oxacillin≤2μg/ml were only resistible to 1—5 of 15 antibitotics.Because of high detection rate of MR-CNS and mutiresistivity,we should pay much attention to MR-CNS infection.AS soon as we find MR-CNS,we should cure it with Vancomycin.