摘要
合成了9种天然抗肿瘤活性萘基木质素山荷叶素的衍生物,通过威廉森醚化法合成了5种醚类衍生物,产率为76%~93%;通过DCC酯缩合法合成了4种苯甲酸酯类衍生物,产率为81%~85%,其结构分别采用1H NMR、13C NMR、HRMS及元素分析测试技术加以证实。
Nine derivatives of natural lignin diphyllin were synthesized. Five ether derivatives were synthe-sized via Williamson etherification with the yields of 76% ~ 93%. Four arylacylester derivatives of diphyllin were synthesized in the presence of DCC with the yields of 81% ~ 85%. These compounds were identified by 1H NMR, 13C NMR, HRMS and elemental analysis.
出处
《应用化学》
CAS
CSCD
北大核心
2008年第11期1315-1319,共5页
Chinese Journal of Applied Chemistry
基金
江苏省科技厅高技术研究计划(BG2007607)
南通大学科研启动基金(08R23)资助项目
关键词
山荷叶素
合成
醚
苯甲酸酯
diphyllin, synthesis, ether, arylacyester