摘要
本院从1992年7月至1996年9月收治经病理检查证实的前列腺癌52例,均行直肠指检(DRE)、B超、血清前列腺酸性磷酸酶(PAP)和前列腺特异抗原(PSA)检查,其诊断前列腺癌阳性率分别为78.8%、50.0%、61.5%、84.6%,PSA阳性率明显高于其它检查(P<0.005),若结合DRE、TRUS(直肠B超),则诊断前列腺癌的敏感性达到96.2%;经直肠前列腺穿刺活检31例,其穿刺阳性率为87.1%。PAP、PSA升高患者的比例与前列腺癌的分期、肿瘤细胞分化程度具相关性。因此,PAP、PSA对前列腺癌的诊断、临床分期、判断预后有较大价值。
From 1992 to 1996,52 cases of prostatic cancer verified by pathological examination had also undertaken DRE, B-ultrasonography, serum PAP and PSA detections, the positive rates were 78.8%, 50.0%, 61.5 %, 84.5% respectively. When PSA detection was used together with DRE and TRUS, the positive rate was as high as 96.2%. We also revealed that the ratio of prostatic cancer with abnormal PAP and PSA was highly related to prostatic cancer stage and cancer cell differentiation. So we concluded PAP and PSA dections are significantly effective in diagnosis, clinical staging and prognosis of prostatic cancer.
