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肠道复合性弥漫性大B细胞淋巴瘤及周围T细胞淋巴瘤临床病理观察 被引量：6

Intestinal composite diffuse large B-cell lymphoma and peripheral T-cell lymphoma:a clinicopathological observation
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摘要 目的探讨罕见的肠道复合性淋巴瘤的临床病理特征。方法采用形态学、免疫组化及分子遗传学方法对1例肠道复合性弥漫性大B细胞淋巴瘤及周围T细胞淋巴瘤进行临床病理分析并复习文献。结果本例肠道复合性B与T细胞淋巴瘤在形态上有弥漫性大B细胞淋巴瘤和非特殊性周围T细胞淋巴瘤的两种区域,免疫组化CD20和CD3(+),分子遗传学上同时有IgH和TCR基因重排。结论肠道复合性淋巴瘤罕见,诊断需结合形态、免疫表型和分子遗传学特征。 Objective To introduce and discuss the clinicopathological features of a rare intestinal composite lymphoma. Methods A case of intestinal composite diffuse large B-cell lymphoma and peripheral T-cell lymphoma was studied by histopathology, immunohistochemistry and molecular genetics with review of the literatures. Results This case of intestinal composite B-and T-cell lymphoma had the area of diffuse large B-cell lymphoma and unspecified peripheral T-cell lymphoma, which expressed CD20 and CD3 separately. IgH and TCR gene rearrangements were also detected. Conclusion Intestinal composite lymphoma is a rare tumor. The diagnosis of intestinal composite lymphoma should be made with combination of morphology, immunophenotype and molecular genetics to avoid misdiagnosis.
作者 水若鸿 周晓燕 罗国培 陆洪芬 许越香 王懿龄 朱雄增
机构地区 复旦大学附属肿瘤医院病理科 复旦大学上海医学院肿瘤系 复旦大学附属华山医院普外科
出处 《诊断病理学杂志》 CSCD 2008年第5期369-372,共4页 Chinese Journal of Diagnostic Pathology
关键词 复合性淋巴瘤 弥漫性大B细胞淋巴瘤 非特殊性周围T细胞淋巴瘤 肠道淋巴瘤 Composite lymphoma Diffuse large B-cell lymphoma Unspecified peripheral T-ceU lymphoma Intestinal lymphoma
分类号 R735.3 [医药卫生—肿瘤]
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参考文献9

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同被引文献44

  • 1吴军,王卓才,陈晓东.复合性淋巴瘤1例报告[J].癌症,2007,26(4):447-447. 被引量：3
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  • 6Yamamoto Y,Yamochi-Onizuka T,Shiozawa E,et al.Discordant lymphoma:MALT lymphoma of the stomach and follicular lymphoma of the parotid gland[J].Pathol Int,2003,53(8):557-562.
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  • 8Goteri G,Rupoli S,Stramazzotti D,et al.Coexistence of two discordant B-cell lymphomas in the skin and lymph node:report of a case with primary cutaneous follicle-center lymphoma and nodal mantle-cell lymphoma[J].Br J Dermatol,2007,157(3):629-631.
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诊断病理学杂志
2008年 第5期

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