摘要
采用牛磺胆酸钠复制大鼠急性出血坏死性胰腺炎模型,动态观察血浆内毒素含量变化。结果发现:随着急性出血坏死性胰腺炎病程的延长,胰腺病理改变加剧,血浆内毒素逐渐升高。提示:内毒素是参与急性出血坏死性胰腺炎病理机制的重要炎性介质之一。
The model of acute hemorrhagic necrotic pancreatitis (AHNP) was produced by retrograde injection of 5% sodium taurocholate into the pancreatic duct. Plasma endotoxin were determined dynamically. The result showed that endotoxin levels become higher accompanied by prolong of AHNP and the pancreatic histologic change become worse. So endotoxin may play an important role in the development of AHNP.
出处
《内蒙古医学院学报》
1997年第4期23-25,共3页
Acta Academiae Medicinae Neimongol
关键词
胰腺炎
内毒素
病理学
大鼠
pancreatitis
endotoxin
pathology
rat