犬甲状腺动脉栓塞术后形态学变化的研究

Morphological study of thyroid gland in dogs after embolization of thyroid artery

为了探讨治疗甲亢的新方法，在对５３条犬甲状腺动脉栓塞过程中，发现有４条犬甲状腺中静脉缺如，有５条犬有甲状腺最下动脉。甲状腺动脉栓塞后，栓塞区域内血流被完全阻断，发生缺血性无茵坏死。术后４个月栓塞区域仍可见栓塞剂存留，病理学检查有大量成纤维细胞增生和炎细胞浸润。甲状腺动脉栓塞后能永久性阻断甲状腺区域血流，栓塞区域血管不能再腔化，有效地降低了甲状腺素的分泌，为治疗甲亢选择新的方法提供了理论依据。

In this experiment we found absence of middle vein in 4 dogs,existence of the lowest artery in 5 dogs, complete arrest of blood stream and ischemic necrosis in the embolized area. Emboli ,mostly consisting of fibroblasts and inflammatory cells,were seen 4 months after the embolization. The embolized thyroid artery persistently obstructs the blood supply of thyroid area,the blood vessel in embolized are. cannot form cavity again,and the secretion of thyroxine reduces effectively. This investigation provides a theoretical basis for a new approach to treating the hyperthyroidism.