椎基底动脉供血不足患者的SPECT脑血流灌注研究

Analysis of Cerebral Blood Flow in Vertebrobasilar Insufficiency by SPECT

目的利用单光子发射计算机断层扫描(SPECT)观察椎基底动脉供血不足(VBI)急性发作期患者局部脑血流灌注(rCBF)情况。方法将临床确诊为VBI患者32例进行SPECT检查,与12名健康体检者同期进行对照观察,分析VBI患者脑血流灌注的情况。结果目测示VBI发作期患者右侧低灌注明显高于左侧,经半定量分析后VBI组的脑血流灌注在多处较对照组减低;VBI组左右比较,右侧脑血流灌注普遍低于左侧。结论SPECT对VBI的诊断有一定价值,且VBI发作期患者脑血流灌注异常在椎基底动脉系为主的基础上还波及颈内动脉系。

Objective To study the cerebral blood flow （rCBF） measured by single photon emission computed tomography （SPECT） during acute episodes of vertebrobasilar insufficiency （VBI）. Methods SPECT examination was performed at acute epi sodes of VBI in 32 patients （pts） with VBI and 12 healthy controls. The rCBF was analyzed and compared. Results The rCBFs were abnormal in pts analyzed by visual examination and semi - quantitative analysis. The hypoperfusion percentage in the right was higher than that in the left obviously. The rCBFs by semi - quantitative analysis in VBI group were lower than that in control group in some areas significantly. Conclusion SPECT was valuable for diagnosis of VBI.