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急性冠脉综合征患者血清肿瘤坏死因子、白介素-6浓度的变化及其临床意义 被引量:2

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摘要 目的观察急性冠脉综合征(ACS)患者血清中炎性细胞因子肿瘤坏死因子及白介素-6的浓度变化及其临床意义。方法采用双抗体夹心ELISA法测定了26例不稳定性心绞痛患者、19例急性心肌梗死患者、21例稳定型心绞痛患者及27例正常对照组血清肿瘤坏死因子-a(TNF-a)及白介素-6(IL-6)的水平。结果不稳定性心绞痛患者及急性心肌梗死患者血清TNF-a和IL-6显著高于稳定型心绞痛及正常对照组。结论TNF-a及IL-6活性增加可能与冠心病的发生与发展有关。外周血TNF-a及IL-6水平在一定程度上可作为冠状动脉粥样硬化斑块的炎症反应程度及不稳定破裂的观察指标。
出处 《延安大学学报(医学科学版)》 2008年第3期20-20,22,共2页 Journal of Yan'an University:Medical Science Edition
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参考文献8

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同被引文献26

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